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YBX1 integration of oncogenic PI3K/mTOR signalling regulates the fitness of malignant epithelial cells

In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are currently missing. An integrated analysis of patient HNC subtypes using single-cell sequencing and proteome profiles reveals an epithelial-mesenchymal transition (EMT) signature within the epithelial cancer-cell pop...

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Detalles Bibliográficos
Autores principales: Bai, Yuchen, Gotz, Carolin, Chincarini, Ginevra, Zhao, Zixuan, Slaney, Clare, Boath, Jarryd, Furic, Luc, Angel, Christopher, Jane, Stephen M., Phillips, Wayne A., Stacker, Steven A., Farah, Camile S., Darido, Charbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033729/
https://www.ncbi.nlm.nih.gov/pubmed/36949044
http://dx.doi.org/10.1038/s41467-023-37161-0