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Hepatic follistatin increases basal metabolic rate and attenuates diet-induced obesity during hepatic insulin resistance

OBJECTIVE: Body weight change and obesity follow the variance of excess energy input balanced against tightly controlled EE (energy expenditure). Since insulin resistance can reduce energy storage, we investigated whether genetic disruption of hepatic insulin signaling reduced adipose mass with incr...

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Detalles Bibliográficos
Autores principales: Tao, Rongya, Stöhr, Oliver, Wang, Caixia, Qiu, Wei, Copps, Kyle D., White, Morris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033741/
https://www.ncbi.nlm.nih.gov/pubmed/36906067
http://dx.doi.org/10.1016/j.molmet.2023.101703