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Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells

Spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and spinal cord injury (SCI). These disorders are currently incurable, while human pluripotent stem cells (hPSCs)-derived spinal motor neurons are p...

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Detalles Bibliográficos
Autores principales: Xu, He Jax, Yao, Yao, Yao, Fenyong, Chen, Jiehui, Li, Meishi, Yang, Xianfa, Li, Sheng, Lu, Fangru, Hu, Ping, He, Shuijin, Peng, Guangdun, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033800/
https://www.ncbi.nlm.nih.gov/pubmed/36949352
http://dx.doi.org/10.1186/s13619-023-00159-6