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Imaging the TGFβ type I receptor in pulmonary arterial hypertension

Transforming growth factor β (TGFβ) activity is perturbed in remodelled pulmonary vasculature of patients with pulmonary arterial hypertension (PAH), cancer, vascular diseases and developmental disorders. Inhibition of TGFβ, which signals via activin receptor-like kinase 5 (ALK5), prevents progressi...

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Detalles Bibliográficos
Autores principales: Rotteveel, Lonneke, Poot, Alex J., Kooijman, Esther J. M., Schuit, Robert C., Schalij, Ingrid, Sun, Xiaoqing, Kurakula, Kondababu, Happé, Chris, Beaino, Wissam, ten Dijke, Peter, Lammertsma, Adriaan A., Bogaard, Harm Jan, Windhorst, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033812/
https://www.ncbi.nlm.nih.gov/pubmed/36947258
http://dx.doi.org/10.1186/s13550-023-00966-7