Modeling of senescent cell dynamics predicts a late‐life decrease in cancer incidence

Current oncogenic theories state that tumors arise from cell lineages that sequentially accumulate (epi)mutations, progressively turning healthy cells into carcinogenic ones. While those models found some empirical support, they are little predictive of intraspecies age‐specific cancer incidence and...

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Detalles Bibliográficos
Autores principales: Bieuville, Margaux, Tissot, Tazzio, Robert, Alexandre, Henry, Pierre‐Yves, Pavard, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033854/
https://www.ncbi.nlm.nih.gov/pubmed/36969142
http://dx.doi.org/10.1111/eva.13514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033854/
https://www.ncbi.nlm.nih.gov/pubmed/36969142
http://dx.doi.org/10.1111/eva.13514

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