Cargando…
Modeling of senescent cell dynamics predicts a late‐life decrease in cancer incidence
Current oncogenic theories state that tumors arise from cell lineages that sequentially accumulate (epi)mutations, progressively turning healthy cells into carcinogenic ones. While those models found some empirical support, they are little predictive of intraspecies age‐specific cancer incidence and...
Autores principales: | Bieuville, Margaux, Tissot, Tazzio, Robert, Alexandre, Henry, Pierre‐Yves, Pavard, Samuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033854/ https://www.ncbi.nlm.nih.gov/pubmed/36969142 http://dx.doi.org/10.1111/eva.13514 |
Ejemplares similares
-
Non-cell-autonomous effects yield lower clonal diversity in expanding tumors
por: Tissot, Tazzio, et al.
Publicado: (2017) -
Cancer risk across mammals
por: Vincze, Orsolya, et al.
Publicado: (2021) -
Flexibility Is Costly: Hidden Physiological Damage From Seasonal Phenotypic Transitions in Heterothermic Species
por: Landes, Julie, et al.
Publicado: (2020) -
Female reproduction bears no survival cost in captivity for gray mouse lemurs
por: Landes, Julie, et al.
Publicado: (2019) -
Negative Selection on BRCA1 Susceptibility Alleles Sheds Light on the Population Genetics of Late-Onset Diseases and Aging Theory
por: Pavard, Samuel, et al.
Publicado: (2007)