CACNA1D overexpression and voltage-gated calcium channels in prostate cancer during androgen deprivation

Prostate cancer is often treated by perturbing androgen receptor signalling. CACNA1D, encoding Ca(V)1.3 ion channels is upregulated in prostate cancer. Here we show how hormone therapy affects CACNA1D expression and Ca(V)1.3 function. Human prostate cells (LNCaP, VCaP, C4-2B, normal RWPE-1) and a ti...

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Detalles Bibliográficos
Autores principales: McKerr, Niamh, Mohd-Sarip, Adone, Dorrian, Hannah, Breen, Conor, A. James, Jacqueline, McQuaid, Stephen, Mills, Ian G., McCloskey, Karen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033880/
https://www.ncbi.nlm.nih.gov/pubmed/36949059
http://dx.doi.org/10.1038/s41598-023-28693-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033880/
https://www.ncbi.nlm.nih.gov/pubmed/36949059
http://dx.doi.org/10.1038/s41598-023-28693-y

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