NTSR1 glycosylation and MMP dependent cleavage generate three distinct forms of the protein

NTSR1 abnormal expression by cancer cells makes it a strategic target for antitumoral therapies, such as compounds that use NTSR1 binding probes to deliver cytotoxic agents to tumor cells. Success of these therapies relies on NTSR1 protein availability and accessibility; therefore, understanding the...

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Detalles Bibliográficos
Autores principales: Libanje, Fotine, Delille, Raphael, Young, Pamela A, Rolland, Sylvie, Meyer-Losic, Florence, Lewkowicz, Elodie, Klinz, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033925/
https://www.ncbi.nlm.nih.gov/pubmed/36949141
http://dx.doi.org/10.1038/s41598-023-31790-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033925/
https://www.ncbi.nlm.nih.gov/pubmed/36949141
http://dx.doi.org/10.1038/s41598-023-31790-7

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