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Synthesis and cloning of long repeat sequences using single-stranded circular DNA

Non-coding repeat expansion causes several neurodegenerative diseases, such as fragile X syndrome, amyotrophic lateral sclerosis/frontotemporal dementia, and spinocerebellar ataxia (SCA31). Such repetitive sequences must be investigated to understand disease mechanisms and prevent them, using novel...

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Detalles Bibliográficos
Autores principales: Bhuiyan, Afsana, Asakawa, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033958/
https://www.ncbi.nlm.nih.gov/pubmed/36970617
http://dx.doi.org/10.3389/fbioe.2023.1115159