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Synthesis and cloning of long repeat sequences using single-stranded circular DNA
Non-coding repeat expansion causes several neurodegenerative diseases, such as fragile X syndrome, amyotrophic lateral sclerosis/frontotemporal dementia, and spinocerebellar ataxia (SCA31). Such repetitive sequences must be investigated to understand disease mechanisms and prevent them, using novel...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033958/ https://www.ncbi.nlm.nih.gov/pubmed/36970617 http://dx.doi.org/10.3389/fbioe.2023.1115159 |