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Striatal fibrinogen extravasation and vascular degeneration correlate with motor dysfunction in an aging mouse model of Alzheimer’s disease

Introduction: Alzheimer’s Disease (AD) patients exhibit signs of motor dysfunction, including gait, locomotion, and balance deficits. Changes in motor function often precede other symptoms of AD as well as correlate with increased severity and mortality. Despite the frequent occurrence of motor dysf...

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Detalles Bibliográficos
Autores principales: Berk-Rauch, Hanna E., Choudhury, Arnab, Richards, Allison T., Singh, Pradeep K., Chen, Zu-Lin, Norris, Erin H., Strickland, Sidney, Ahn, Hyung Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034037/
https://www.ncbi.nlm.nih.gov/pubmed/36967821
http://dx.doi.org/10.3389/fnagi.2023.1064178