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Pan-cancer investigation of C-to-U editing reveals its important role in cancer development and new targets for cancer treatment

RNA editing is prevalent in the transcriptome and is important for multiple cellular processes. C-to-U RNA editing sites (RES) are relatively rare and understudied in humans, compared to A-to-I editing. However, the functional impact of C-to-U editing in human cancers also remains elusive. Here, we...

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Detalles Bibliográficos
Autores principales: Guo, Mengbiao, Li, Feng, Zhao, Linghao, Fang, Zhengwen, Yu, Huichuan, Songyang, Zhou, Xiong, Yuanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034049/
https://www.ncbi.nlm.nih.gov/pubmed/36969056
http://dx.doi.org/10.3389/fonc.2023.1097667