Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands

INTRODUCTION: The apelin receptor binds two distinct endogenous peptides, apelin and ELA, which act in an autocrine/paracrine manner to regulate the human cardiovascular system. As a class A GPCR, targeting the apelin receptor is an attractive therapeutic strategy. With improvements in imaging techn...

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Detalles Bibliográficos
Autores principales: Williams, Thomas L., Macrae, Robyn G. C., Kuc, Rhoda E., Brown, Alastair J. H., Maguire, Janet J., Davenport, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034064/
https://www.ncbi.nlm.nih.gov/pubmed/36967803
http://dx.doi.org/10.3389/fendo.2023.1139121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034064/
https://www.ncbi.nlm.nih.gov/pubmed/36967803
http://dx.doi.org/10.3389/fendo.2023.1139121

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