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Erectile dysfunction and exosome therapy
Erectile dysfunction (ED), as a common male disease, can seriously reduce the life quality of men and their partners. With the improvement of human living standards, ED is considered to be an important health issue that plagues men. However, it is difficult for existing therapeutic approaches to mee...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034068/ https://www.ncbi.nlm.nih.gov/pubmed/36967787 http://dx.doi.org/10.3389/fendo.2023.1123383 |
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author | Feng, Huan Peng, Wei Deng, Zhiyao Liu, Jihong Wang, Tao |
author_facet | Feng, Huan Peng, Wei Deng, Zhiyao Liu, Jihong Wang, Tao |
author_sort | Feng, Huan |
collection | PubMed |
description | Erectile dysfunction (ED), as a common male disease, can seriously reduce the life quality of men and their partners. With the improvement of human living standards, ED is considered to be an important health issue that plagues men. However, it is difficult for existing therapeutic approaches to meet the needs of all patients, so it is necessary to develop novel treatment strategies. Exosomes, as a class of vesicles secreted by cells with bilayer membrane structure, are involved in various physiological and pathological processes in human body and considered to have great therapeutic potentials. This review summarizes the recent advances on exosome therapy with animal models of ED, and proposes the prospect of future research in order to provide a basis for clinical trials and clinical translation. |
format | Online Article Text |
id | pubmed-10034068 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100340682023-03-24 Erectile dysfunction and exosome therapy Feng, Huan Peng, Wei Deng, Zhiyao Liu, Jihong Wang, Tao Front Endocrinol (Lausanne) Endocrinology Erectile dysfunction (ED), as a common male disease, can seriously reduce the life quality of men and their partners. With the improvement of human living standards, ED is considered to be an important health issue that plagues men. However, it is difficult for existing therapeutic approaches to meet the needs of all patients, so it is necessary to develop novel treatment strategies. Exosomes, as a class of vesicles secreted by cells with bilayer membrane structure, are involved in various physiological and pathological processes in human body and considered to have great therapeutic potentials. This review summarizes the recent advances on exosome therapy with animal models of ED, and proposes the prospect of future research in order to provide a basis for clinical trials and clinical translation. Frontiers Media S.A. 2023-03-09 /pmc/articles/PMC10034068/ /pubmed/36967787 http://dx.doi.org/10.3389/fendo.2023.1123383 Text en Copyright © 2023 Feng, Peng, Deng, Liu and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Endocrinology Feng, Huan Peng, Wei Deng, Zhiyao Liu, Jihong Wang, Tao Erectile dysfunction and exosome therapy |
title | Erectile dysfunction and exosome therapy |
title_full | Erectile dysfunction and exosome therapy |
title_fullStr | Erectile dysfunction and exosome therapy |
title_full_unstemmed | Erectile dysfunction and exosome therapy |
title_short | Erectile dysfunction and exosome therapy |
title_sort | erectile dysfunction and exosome therapy |
topic | Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034068/ https://www.ncbi.nlm.nih.gov/pubmed/36967787 http://dx.doi.org/10.3389/fendo.2023.1123383 |
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