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Mechanisms underlying TDP-43 pathology and neurodegeneration: An updated Mini-Review

TAR DNA binding protein 43 kDa (TDP-43) plays an important role in several essential cell functions. However, TDP-43 dysfunction has been implicated in the development of various brain diseases including amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), and limbic predom...

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Detalles Bibliográficos
Autores principales: Nilaver, Benjamin I., Urbanski, Henryk F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034072/
https://www.ncbi.nlm.nih.gov/pubmed/36967829
http://dx.doi.org/10.3389/fnagi.2023.1142617