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Off-target effects in CRISPR/Cas9 gene editing

Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence. With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising t...

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Detalles Bibliográficos
Autores principales: Guo, Congting, Ma, Xiaoteng, Gao, Fei, Guo, Yuxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034092/
https://www.ncbi.nlm.nih.gov/pubmed/36970624
http://dx.doi.org/10.3389/fbioe.2023.1143157