Phosphorylation of pICln by the autophagy activating kinase ULK1 regulates snRNP biogenesis and splice activity of the cell

The spliceosome, responsible for all mature protein-coding transcripts of eukaryotic intron-containing genes, consists of small uridine-rich nuclear ribonucleoproteins (UsnRNPs). The assembly of UsnRNPs depends, on one hand, on the arginine methylation of Sm proteins catalyzed by the PRMT5 complex....

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Detalles Bibliográficos
Autores principales: Esser, Lea Marie, Schmitz, Katharina, Hillebrand, Frank, Erkelenz, Steffen, Schaal, Heiner, Stork, Björn, Grimmler, Matthias, Wesselborg, Sebastian, Peter, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034211/
https://www.ncbi.nlm.nih.gov/pubmed/36968021
http://dx.doi.org/10.1016/j.csbj.2023.03.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034211/
https://www.ncbi.nlm.nih.gov/pubmed/36968021
http://dx.doi.org/10.1016/j.csbj.2023.03.015

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