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Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics

Hearing impairment is the most common sensory disorder in humans, and yet hardly any medications are licensed for the treatment of inner ear pathologies. Intricate pharmacokinetic examinations to better understand drug distribution within this complex organ could facilitate the development of novel...

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Detalles Bibliográficos
Autores principales: Yildiz, Erdem, Gadenstaetter, Anselm J., Gerlitz, Matthias, Landegger, Lukas D., Liepins, Rudolfs, Nieratschker, Michael, Glueckert, Rudolf, Staecker, Hinrich, Honeder, Clemens, Arnoldner, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034346/
https://www.ncbi.nlm.nih.gov/pubmed/36969846
http://dx.doi.org/10.3389/fphar.2023.1062379