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Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics
Hearing impairment is the most common sensory disorder in humans, and yet hardly any medications are licensed for the treatment of inner ear pathologies. Intricate pharmacokinetic examinations to better understand drug distribution within this complex organ could facilitate the development of novel...
Autores principales: | Yildiz, Erdem, Gadenstaetter, Anselm J., Gerlitz, Matthias, Landegger, Lukas D., Liepins, Rudolfs, Nieratschker, Michael, Glueckert, Rudolf, Staecker, Hinrich, Honeder, Clemens, Arnoldner, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034346/ https://www.ncbi.nlm.nih.gov/pubmed/36969846 http://dx.doi.org/10.3389/fphar.2023.1062379 |
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