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A cis-element at the Rorc locus regulates the development of type 3 innate lymphoid cells

BACKGROUND: As an important early source of IL-17A and IL-22 in immune responses, type 3 innate lymphoid cells (ILC3s) are critically regulated by the transcription factor retinoic-acid-receptor-related orphan receptor gamma t (RORγt). Previously, we have identified a crucial role of the conserved n...

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Detalles Bibliográficos
Autores principales: Chang, Dehui, Zhang, Hao, Ge, Jing, Xing, Qi, Guo, Xinyi, Wang, Xiaohu, Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034404/
https://www.ncbi.nlm.nih.gov/pubmed/36969227
http://dx.doi.org/10.3389/fimmu.2023.1105145