The interplay between GPIb/IX antibodies, platelet hepatic sequestration, and TPO levels in patients with chronic ITP

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with an incompletely understood pathophysiology but includes platelet-clearance in the spleen and liver via T cells and/or platelet autoantibodies. Strikingly, thrombopoietin (TPO) levels remain low in ITP. Platelet-glycoprotein (GP)Ib...

Descripción completa

Detalles Bibliográficos
Autores principales: Amini, Sufia N., Nelson, Vivianne S., Porcelijn, Leendert, Netelenbos, Tanja, Zwaginga, Jaap Jan, de Haas, Masja, Schipperus, Martin R., Kapur, Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034565/
https://www.ncbi.nlm.nih.gov/pubmed/35901281
http://dx.doi.org/10.1182/bloodadvances.2022007751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034565/
https://www.ncbi.nlm.nih.gov/pubmed/35901281
http://dx.doi.org/10.1182/bloodadvances.2022007751

Ejemplares similares