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The interplay between GPIb/IX antibodies, platelet hepatic sequestration, and TPO levels in patients with chronic ITP

Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder with an incompletely understood pathophysiology but includes platelet-clearance in the spleen and liver via T cells and/or platelet autoantibodies. Strikingly, thrombopoietin (TPO) levels remain low in ITP. Platelet-glycoprotein (GP)Ib...

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Detalles Bibliográficos
Autores principales:	Amini, Sufia N., Nelson, Vivianne S., Porcelijn, Leendert, Netelenbos, Tanja, Zwaginga, Jaap Jan, de Haas, Masja, Schipperus, Martin R., Kapur, Rick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2022
Materias:	Stimulus Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034565/ https://www.ncbi.nlm.nih.gov/pubmed/35901281 http://dx.doi.org/10.1182/bloodadvances.2022007751

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