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Babesia microti Variant With Multiple Resistance Mutations Detected in an Immunocompromised Patient Receiving Atovaquone Prophylaxis

We report Babesia microti genomic sequences with multiple mutations in the atovaquone-target region of cytochrome b, including a newly identified Y272S mutation, plus 1 mutation of undetermined significance in the azithromycin-associated ribosomal protein L4. The parasite was sequenced from an immun...

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Detalles Bibliográficos
Autores principales: Holbrook, Nolan R, Klontz, Erik H, Adams, Gordon C, Schnittman, Samuel R, Issa, Nicolas C, Bond, Sheila A, Branda, John A, Lemieux, Jacob E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034591/
https://www.ncbi.nlm.nih.gov/pubmed/36968958
http://dx.doi.org/10.1093/ofid/ofad097