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First‐in‐human application of double‐stranded RNA bacteriophage in the treatment of pulmonary Pseudomonas aeruginosa infection

A double‐stranded RNA (dsRNA) phage phiYY is able to kill a pyomelanin‐producing Pseudomonas aeruginosa strain, which was isolated from a 40‐year‐old man with interstitial lung disease (ILD) and chronic lung infection. Phage therapy was used as a last resort for this patient. The three‐course nebuli...

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Detalles Bibliográficos
Autores principales: Li, Linlin, Zhong, Qiu, Zhao, Yunze, Bao, Juan, Liu, Bing, Zhong, Zhuojun, Wang, Jing, Yang, Lan, Zhang, Tingting, Cheng, Mengjun, Wu, Nannan, Zhu, Tongyu, Le, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034620/
https://www.ncbi.nlm.nih.gov/pubmed/36636832
http://dx.doi.org/10.1111/1751-7915.14217