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Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway

Acute lung injury (ALI) is a life-threatening disease with high incidence and mortality rates. Urolithin A (UA) is a pomegranate intestinal flora metabolite with anti-inflammatory, antioxidant, and anti-aging properties. Ferroptosis is a critical factor in lipopolysaccharide (LPS)-induced acute lung...

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Detalles Bibliográficos
Autores principales: Lou, Lejing, Wang, Min, He, Jingjing, Yang, Song, Meng, Fanxi, Wang, Shijia, Jin, Xiao, Cai, Jihao, Cai, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034769/
https://www.ncbi.nlm.nih.gov/pubmed/36969874
http://dx.doi.org/10.3389/fphar.2023.1067402