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Fuzzy Drug Targets: Disordered Proteins in the Drug-Discovery Realm

[Image: see text] Intrinsically disordered proteins (IDPs) and regions (IDRs) form a large part of the eukaryotic proteome. Contrary to the structure–function paradigm, the disordered proteins perform a myriad of functions in vivo. Consequently, they are involved in various disease pathways and are...

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Detalles Bibliográficos
Autores principales: Saurabh, Suman, Nadendla, Karthik, Purohit, Shubh Sanket, Sivakumar, Ponnurengam Malliappan, Cetinel, Sibel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034788/
https://www.ncbi.nlm.nih.gov/pubmed/36969402
http://dx.doi.org/10.1021/acsomega.2c07708