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Fuzzy Drug Targets: Disordered Proteins in the Drug-Discovery Realm
[Image: see text] Intrinsically disordered proteins (IDPs) and regions (IDRs) form a large part of the eukaryotic proteome. Contrary to the structure–function paradigm, the disordered proteins perform a myriad of functions in vivo. Consequently, they are involved in various disease pathways and are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034788/ https://www.ncbi.nlm.nih.gov/pubmed/36969402 http://dx.doi.org/10.1021/acsomega.2c07708 |