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Adenosine monophosphate deaminase in the endoplasmic reticulum–mitochondria interface promotes mitochondrial Ca(2+) overload in type 2 diabetes rat hearts

AIMS/INTRODUCTION: We previously showed that upregulation of myocardial adenosine monophosphate deaminase (AMPD) is associated with pressure overload‐induced diastolic dysfunction in type 2 diabetes hearts. Here, we examined involvement of AMPD localized in the endoplasmic reticulum–mitochondria int...

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Detalles Bibliográficos
Autores principales: Osanami, Arata, Sato, Tatsuya, Toda, Yuki, Shimizu, Masaki, Kuno, Atsushi, Kouzu, Hidemichi, Yano, Toshiyuki, Ohwada, Wataru, Ogawa, Toshifumi, Miura, Tetsuji, Tanno, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034956/
https://www.ncbi.nlm.nih.gov/pubmed/36815317
http://dx.doi.org/10.1111/jdi.13982