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Benchtop (19)F Nuclear Magnetic Resonance (NMR) Spectroscopy Provides Mechanistic Insight into the Biginelli Condensation toward the Chemical Synthesis of Novel Trifluorinated Dihydro- and Tetrahydropyrimidinones as Antiproliferative Agents

[Image: see text] Benchtop nuclear magnetic resonance (NMR) spectroscopy has enabled the monitoring and optimization of chemical transformations while simultaneously providing kinetic, mechanistic, and structural insight into reaction pathways with quantitative precision. Moreover, benchtop NMR prot...

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Detalles Bibliográficos
Autores principales: Chen, Rosie, Singh, Pratyush, Su, Sarah, Kocalar, Selin, Wang, Xina, Mandava, Neha, Venkatesan, Srishti, Ferguson, Adrienne, Rao, Aishi, Le, Emma, Rojas, Casey, Njoo, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034998/
https://www.ncbi.nlm.nih.gov/pubmed/36969393
http://dx.doi.org/10.1021/acsomega.3c00290