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Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation

[Image: see text] Advanced glycation end-products (AGEs) are irreversible protein modifications that are strongly associated with aging and disease. Recently, the Parkinsonism-associated protein DJ-1 has been reported to exhibit deglycase activity that erases early glycation intermediates and stable...

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Detalles Bibliográficos
Autores principales: Gao, Qingzeng, Jacob-Dolan, Jeremiah W., Scheck, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035033/
https://www.ncbi.nlm.nih.gov/pubmed/36820886
http://dx.doi.org/10.1021/acs.biochem.3c00028