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Addressing Transcriptional Dysregulation in Cancer through CDK9 Inhibition

[Image: see text] Undermining transcriptional addiction, the dependence of cancers on selected transcriptional programs, is critically important for addressing cancers with high unmet clinical need. Cyclin-dependent kinase 9 (CDK9) has long been considered an actionable therapeutic target for modula...

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Detalles Bibliográficos
Autores principales: Toure, Mohammed A., Koehler, Angela N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035036/
https://www.ncbi.nlm.nih.gov/pubmed/36854448
http://dx.doi.org/10.1021/acs.biochem.2c00609