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Human cortical spheroids with a high diversity of innately developing brain cell types

BACKGROUND: Three-dimensional (3D) human brain spheroids are instrumental to study central nervous system (CNS) development and (dys)function. Yet, in current brain spheroid models the limited variety of cell types hampers an integrated exploration of CNS (disease) mechanisms. METHODS: Here we repor...

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Detalles Bibliográficos
Autores principales: De Kleijn, Kim M. A., Zuure, Wieteke A., Straasheijm, Kirsten R., Martens, Marijn B., Avramut, M. Cristina, Koning, Roman I., Martens, Gerard J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035191/
https://www.ncbi.nlm.nih.gov/pubmed/36959625
http://dx.doi.org/10.1186/s13287-023-03261-3