Localized microglia dysregulation impairs central nervous system myelination in development

Myelination of neuronal axons is a critical aspect of central nervous system development and function. However, the fundamental cellular and molecular mechanisms influencing human developmental myelination and its failure are not fully understood. Here, we used digital spatial transcriptomics of a r...

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Detalles Bibliográficos
Autores principales: Holloway, Rebecca K., Zhang, Liang, Molina-Gonzalez, Irene, Ton, Kathy, Nicoll, James A. R., Boardman, James P., Liang, Yan, Williams, Anna, Miron, Veronique E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035254/
https://www.ncbi.nlm.nih.gov/pubmed/36949514
http://dx.doi.org/10.1186/s40478-023-01543-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035254/
https://www.ncbi.nlm.nih.gov/pubmed/36949514
http://dx.doi.org/10.1186/s40478-023-01543-8

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