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The IL-33:ST2 axis is unlikely to play a central fibrogenic role in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease (ILD) with limited treatment options. Interleukin-33 (IL-33) is proposed to play a role in the development of IPF however the exclusive use of prophylactic dosing regimens means that the therapeutic benefit of...

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Detalles Bibliográficos
Autores principales: Stephenson, Katherine E., Porte, Joanne, Kelly, Aoife, Wallace, William A., Huntington, Catherine E., Overed-Sayer, Catherine L., Cohen, E. Suzanne, Jenkins, R. Gisli, John, Alison E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035257/
https://www.ncbi.nlm.nih.gov/pubmed/36949463
http://dx.doi.org/10.1186/s12931-023-02334-4