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Comprehensive Characterization of the Multiple Myeloma Immune Microenvironment Using Integrated scRNA-seq, CyTOF, and CITE-seq Analysis

As part of the Multiple Myeloma Research Foundation (MMRF) immune atlas pilot project, we compared immune cells of multiple myeloma bone marrow samples from 18 patients assessed by single-cell RNA sequencing (scRNA-seq), mass cytometry (CyTOF), and cellular indexing of transcriptomes and epitopes by...

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Detalles Bibliográficos
Autores principales: Yao, Lijun, Jayasinghe, Reyka G., Lee, Brian H., Bhasin, Swati S., Pilcher, William, Doxie, Deon Bryant, Gonzalez-Kozlova, Edgar, Dasari, Surendra, Fiala, Mark A., Pita-Juarez, Yered, Strausbauch, Michael, Kelly, Geoffrey, Thomas, Beena E., Kumar, Shaji K., Cho, Hearn Jay, Anderson, Emilie, Wendl, Michael C., Dawson, Travis, D'souza, Darwin, Oh, Stephen T., Cheloni, Giulia, Li, Ying, DiPersio, John F., Rahman, Adeeb H., Dhodapkar, Kavita M., Kim-Schulze, Seunghee, Vij, Ravi, Vlachos, Ioannis S., Mehr, Shaadi, Hamilton, Mark, Auclair, Daniel, Kourelis, Taxiarchis, Avigan, David, Dhodapkar, Madhav V., Gnjatic, Sacha, Bhasin, Manoj K., Ding, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035369/
https://www.ncbi.nlm.nih.gov/pubmed/36969740
http://dx.doi.org/10.1158/2767-9764.CRC-22-0022