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Circulating IgA Antibodies Against Fusobacterium nucleatum Amyloid Adhesin FadA are a Potential Biomarker for Colorectal Neoplasia

Fusobacterium nucleatum (Fn) is a gram-negative oral anaerobe and prevalent in colorectal cancer. Fn encodes a unique amyloid-like adhesin, FadA complex (FadAc), consisting of intact pre-FadA and cleaved mature FadA, to promote colorectal cancer tumorigenesis. We aimed to evaluate circulating anti-F...

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Detalles Bibliográficos
Autores principales: Baik, Jung Eun, Li, Li, Shah, Manish A., Freedberg, Daniel E., Jin, Zhezhen, Wang, Timothy C., Han, Yiping W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035380/
https://www.ncbi.nlm.nih.gov/pubmed/36970057
http://dx.doi.org/10.1158/2767-9764.CRC-22-0248