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Multiregional Sequencing Analysis Reveals Extensive Genetic Heterogeneity in Gastric Tumors from Latinos

Gastric cancer is a leading cause of cancer mortality and health disparities in Latinos. We evaluated gastric intratumoral heterogeneity using multiregional sequencing of >700 cancer genes in 115 tumor biopsies from 32 patients, 29 who were Latinos. Analyses focused on comparisons with The Cancer...

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Detalles Bibliográficos
Autores principales: Toal, Ted W., Estrada-Florez, Ana P., Polanco-Echeverry, Guadalupe M., Sahasrabudhe, Ruta M., Lott, Paul C., Suarez-Olaya, John J., Guevara-Tique, Alix A., Rocha, Sienna, Morales-Arana, Alexa, Castro-Valencia, Fabian, Urayama, Shiro, Kirane, Amanda, Wei, Dongguang, Rios-Sarabia, Nora, Medrano, Rafael, Mantilla, Alejandra, Echeverry de Polanco, Magdalena, Torres, Javier, Bohorquez-Lozano, Mabel E., Carvajal-Carmona, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035402/
https://www.ncbi.nlm.nih.gov/pubmed/36970058
http://dx.doi.org/10.1158/2767-9764.CRC-22-0149