Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy

Although immune checkpoint inhibitors targeting T-cell immunoregulatory proteins have revolutionized cancer treatment, they are effective only in a limited number of patients, and new strategies are needed to enhance tumor responses to immunotherapies. Deletion of protein tyrosine phosphatase non-re...

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Detalles Bibliográficos
Autores principales: Zhu, Zhouting, Tang, Rachel, Huff, Sarah, Kummetha, Indrasena Reddy, Wang, Lingling, Li, Na, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035454/
https://www.ncbi.nlm.nih.gov/pubmed/36968224
http://dx.doi.org/10.1158/2767-9764.CRC-21-0186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035454/
https://www.ncbi.nlm.nih.gov/pubmed/36968224
http://dx.doi.org/10.1158/2767-9764.CRC-21-0186

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