Improving expression and assembly of difficult-to-express heterologous proteins in Saccharomyces cerevisiae by culturing at a sub-physiological temperature

BACKGROUND: Escherichia coli heat labile toxin B subunit (LTB) is one of the most popular oral vaccine adjuvants and intestine adsorption enhancers. It is often expressed as a fusion partner with target antigens to enhance their immunogenicity as well as gut absorbability. However, high expression l...

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Detalles Bibliográficos
Autores principales: So, Kum-Kang, Le, Ngoc My Tieu, Nguyen, Ngoc-Luong, Kim, Dae-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035479/
https://www.ncbi.nlm.nih.gov/pubmed/36959657
http://dx.doi.org/10.1186/s12934-023-02065-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035479/
https://www.ncbi.nlm.nih.gov/pubmed/36959657
http://dx.doi.org/10.1186/s12934-023-02065-7

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