A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases

Disease recurrence and drug resistance are major challenges in the clinical management of patients with colorectal cancer liver metastases (CLM), and because tumors are generally microsatellite stable (MSS), responses to immune therapies are poor. The mesenchymal phenotype is overrepresented in trea...

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Detalles Bibliográficos
Autores principales: Nygaard, Vigdis, Ree, Anne Hansen, Dagenborg, Vegar Johansen, Børresen-Dale, Anne-Lise, Edwin, Bjørn, Fretland, Åsmund Avdem, Grzyb, Krzysztof, Haugen, Mads H., Mælandsmo, Gunhild M., Flatmark, Kjersti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035516/
https://www.ncbi.nlm.nih.gov/pubmed/36968142
http://dx.doi.org/10.1158/2767-9764.CRC-22-0295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035516/
https://www.ncbi.nlm.nih.gov/pubmed/36968142
http://dx.doi.org/10.1158/2767-9764.CRC-22-0295

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