Targeting Lymphoma-associated Macrophage Expansion via CSF1R/JAK Inhibition is a Therapeutic Vulnerability in Peripheral T-cell Lymphomas

The reciprocal relationship between malignant T cells and lymphoma-associated macrophages (LAM) within the tumor microenvironment (TME) is unique, as LAMs are well poised to provide ligands for antigen, costimulatory, and cytokine receptors that promote T-cell lymphoma growth. Conversely, malignant...

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Detalles Bibliográficos
Autores principales: Gao, Xin, Kady, Nermin, Wang, Chenguang, Abdelrahman, Suhaib, Gann, Peter, Sverdlov, Maria, Wolfe, Ashley, Brown, Noah, Reneau, John, Robida, Aaron M., Murga-Zamalloa, Carlos, Wilcox, Ryan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035520/
https://www.ncbi.nlm.nih.gov/pubmed/36970721
http://dx.doi.org/10.1158/2767-9764.CRC-22-0336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035520/
https://www.ncbi.nlm.nih.gov/pubmed/36970721
http://dx.doi.org/10.1158/2767-9764.CRC-22-0336

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