Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction

When breast cancer metastasizes to bone, treatment options are limited. Failure to treat bone metastases is thought to be due to therapy-resistant features of the bone marrow microenvironment. Using a murine model of bone metastatic mammary carcinoma, we demonstrate that systemic delivery of polymer...

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Detalles Bibliográficos
Autores principales: Florian, David C., Bennett, Natalie E., Odziomek, Mateusz, Baljon, Jessalyn J., Wehbe, Mohamed, Merkel, Alyssa R., Fischer, Melissa A., Savona, Michael R., Rhoades, Julie A., Guelcher, Scott A., Wilson, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035525/
https://www.ncbi.nlm.nih.gov/pubmed/36968140
http://dx.doi.org/10.1158/2767-9764.CRC-22-0180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035525/
https://www.ncbi.nlm.nih.gov/pubmed/36968140
http://dx.doi.org/10.1158/2767-9764.CRC-22-0180

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