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Role of regulation of PD-1 and PD-L1 expression in sepsis

Long term immunosuppression is problematic during sepsis. The PD-1 and PD-L1 immune checkpoint proteins have potent immunosuppressive functions. Recent studies have revealed several features of PD-1 and PD-L1 and their roles in sepsis. Here, we summarize the overall findings of PD-1 and PD-L1 by fir...

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Detalles Bibliográficos
Autores principales: Zhang, Teng, Yu-Jing, Li, Ma, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035551/
https://www.ncbi.nlm.nih.gov/pubmed/36969168
http://dx.doi.org/10.3389/fimmu.2023.1029438