Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy

INTRODUCTION: Diabetes is a global disease, commonly complicated by neuropathy. The spinal cord reacts to diabetes by neuronal apoptosis, microglial activation, and astrocytosis, with a disturbance in neuronal and glial Nuclear factor erythroid 2-related factor/Heme oxygenase-1 (Nrf2/HO-1) and Nucle...

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Detalles Bibliográficos
Autores principales: Elsayed, Hassan Reda Hassan, Rabei, Mohammed R., Elshaer, Mohamed Mahmoud Abdelraheem, El Nashar, Eman Mohamad, Alghamdi, Mansour Abdullah, Al-Qahtani, Zainah, Nabawy, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroanatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035597/
https://www.ncbi.nlm.nih.gov/pubmed/36968023
http://dx.doi.org/10.3389/fnana.2023.1094301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035597/
https://www.ncbi.nlm.nih.gov/pubmed/36968023
http://dx.doi.org/10.3389/fnana.2023.1094301

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