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The dual role of transforming growth factor-beta signatures in human B viral multistep hepatocarcinogenesis: early and late responsive genes

BACKGROUND/AIM: Transforming growth factor-beta (TGF-β) has a dichotomous role, functioning as a tumor suppressor and tumor promoter. TGF-β signatures, explored in mouse hepatocytes, have been reported to predict the clinical outcomes of hepatocellular carcinoma (HCC) patients; HCCs exhibiting early...

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Detalles Bibliográficos
Autores principales: Yoo, Jeong Eun, Nahm, Ji Hae, Kim, Young-Joo, Jeon, Youngsic, Park, Young Nyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Liver Cancer Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035736/
https://www.ncbi.nlm.nih.gov/pubmed/37383409
http://dx.doi.org/10.17998/jlc.2022.04.20