Modulating the Kynurenine pathway or sequestering toxic 3-hydroxykynurenine protects the retina from light-induced damage in Drosophila

Tissue health is regulated by a myriad of exogenous or endogenous factors. Here we investigated the role of the conserved Kynurenine pathway (KP) in maintaining retinal homeostasis in the context of light stress in Drosophila melanogaster. cinnabar, cardinal and scarlet are fly genes that encode dif...

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Detalles Bibliográficos
Autores principales: Hebbar, Sarita, Traikov, Sofia, Hälsig, Catrin, Knust, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035932/
https://www.ncbi.nlm.nih.gov/pubmed/36952572
http://dx.doi.org/10.1371/journal.pgen.1010644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035932/
https://www.ncbi.nlm.nih.gov/pubmed/36952572
http://dx.doi.org/10.1371/journal.pgen.1010644

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