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Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

As part of our ongoing endeavour to identify novel inhibitors of cancer-associated CA isoforms IX and XII as possible anticancer candidates, here we describe the design and synthesis of small library of 2-aryl-quinazolin-4-yl aminobenzoic acid derivatives (6a–c, 7a–c, and 8a–c) as new non-classical...

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Detalles Bibliográficos
Autores principales: Elsayed, Zainab M., Almahli, Hadia, Nocentini, Alessio, Ammara, Andrea, Supuran, Claudiu T., Eldehna, Wagdy M., Abou-Seri, Sahar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035947/
https://www.ncbi.nlm.nih.gov/pubmed/36942698
http://dx.doi.org/10.1080/14756366.2023.2191163