Triptolide protects against podocyte injury in diabetic nephropathy by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome pathway

Objectives: Diabetic nephropathy (DN) is the most common microvascular complication of diabetes mellitus. This study investigated the mechanism of triptolide (TP) in podocyte injury in DN. Methods: DN mouse models were established by feeding with a high-fat diet and injecting with streptozocin and M...

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Detalles Bibliográficos
Autores principales: Lv, Chenlei, Cheng, Tianyang, Zhang, Bingbing, Sun, Ke, Lu, Keda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035962/
https://www.ncbi.nlm.nih.gov/pubmed/36938748
http://dx.doi.org/10.1080/0886022X.2023.2165103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035962/
https://www.ncbi.nlm.nih.gov/pubmed/36938748
http://dx.doi.org/10.1080/0886022X.2023.2165103

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