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Triptolide protects against podocyte injury in diabetic nephropathy by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome pathway

Objectives: Diabetic nephropathy (DN) is the most common microvascular complication of diabetes mellitus. This study investigated the mechanism of triptolide (TP) in podocyte injury in DN. Methods: DN mouse models were established by feeding with a high-fat diet and injecting with streptozocin and M...

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Detalles Bibliográficos
Autores principales:	Lv, Chenlei, Cheng, Tianyang, Zhang, Bingbing, Sun, Ke, Lu, Keda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035962/ https://www.ncbi.nlm.nih.gov/pubmed/36938748 http://dx.doi.org/10.1080/0886022X.2023.2165103

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