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Implication of E3 ligase RAD18 in UV-induced mutagenesis in human induced pluripotent stem cells and neuronal progenitor cells

Pluripotent stem cells (PSCs) have the potential to differentiate to any of the other organs. The genome DNA integrity of PSCs is maintained by a high level of transcription for a number of genes involved in DNA repair, cell cycle and apoptosis. However, it remains unclear how high the frequency of...

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Detalles Bibliográficos
Autores principales: Shimada, Mikio, Tokumiya, Takumi, Miyake, Tomoko, Tsukada, Kaima, Kanzaki, Norie, Yanagihara, Hiromi, Kobayashi, Junya, Matsumoto, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036092/
https://www.ncbi.nlm.nih.gov/pubmed/36634340
http://dx.doi.org/10.1093/jrr/rrac099